Archive for July, 2011

What is Mesothelioma?

Mesothelioma can either be malignant (cancerous) or benign (non-cancerous) in nature. Mesothelioma affects the mesothelium, hence mesothelioma. What is the mesothelium?

The mesothelium is a type of tissue lined with special cells referred to as mesothelial cells. The mesothelial cells typically line the abdominal cavity, heart cavity, chest cavity, and the outer surface of most internal organs. Each cavity has a specific name for the mesothelial covered cavity which is:

  • Peritoneum: abdominal cavity
  • Pleura: chest cavity
  • Pericardium: heart cavity

The mesothelium has a specific purpose in the body. The mesothelium produces a lubricating fluid that allows easy movement of the organs. The pleural mesothelium for example, allows the lungs to move easily with each breath that is taken. Without this, breathing would be a difficult and possibly painful process.Many refer to malignant mesothelioma as simply, mesothelioma. There are three main types of malignant mesothelioma ranked from less likely to more commonly seen:

  1. Sarcomatoid
  2. Mixed/Biphasic
  3. Epithelioid

Malignant mesothelioma more commonly begins in the chest cavity (pleural mesothelioma). Approximately 10-20% of the cases of malignant mesothelioma will begin in the abdominal cavity (peritoneal mesothelioma). Malignant mesothelioma rarely begins in the cavity surrounding the heart (pericardial mesothelioma).Malignant Mesothelioma Statistics:

Mesothelioma is a very rare cancer estimated to affect 2,000-3,000 newly diagnosed cases annually in the U.S. The United States reported an increased rate of mesothelioma from 1970 to 1990, which has currently stabilized and possibly decreased. However, European countries continue to see an increase in the rate of mesothelioma.

Mesothelioma is commonly seen in the ages 65 years and older but increases with age. Mesothelioma is 5 times more likely to affect men than women. Mesothelioma is more common in the Caucasian nationality than African American.

Mesothelioma is a very serious cancer. Symptoms commonly do not appear early which causes mesothelioma to be diagnosed at an advanced stage. For this reason, mesothelioma has a low survival rate that is about 1-2 years. However, cancer research is slowly changing this statistic. Learn more about what risk factors predispose you to mesothelioma.

Symptoms That Help You Identify Mesothelioma

Mesothelioma can only be identified with help of its symptoms which appear after 20-50 years the person has developed the disease. Symptoms of mesothelioma appear when you have been exposed to the deadly toxic asbestos decades back. By the time they appear, they have already spread to all parts of the body.

There are 3 major types of mesothelioma which attack the body with some similar symptoms. These types of mesothelioma along with their symptoms are:

Pleural Mesothelioma

Pleural mesothelioma attacks the lining of the lungs and causes various symptoms. These symptoms include:

  • Cough
  • Difficulty sleeping
  • Fever
  • Pain at the side of the chest or the lower back
  • Pleural effusions (fluid in the chest cavity)
  • Progressive loss of appetite and weight loss
  • Dyspnea
  • Tiredness
  • Trouble swallowing
  • Muscle weakness
  • Sensory loss
  • Nausea
  • Pleural effusion is an accumulation of fluid between the lining of the lung and the chest cavity. It is one of most common symptoms of mesothelioma and leads to shortness of breath. As the fluid collects in the lining of the lungs and chest, the pain and shortness of breath also increase. Dyspnea is shortness of breath which can be caused by a pleural effusion and/or by the presence of a tumor in the pleura or the lining of the lungs.

    A buildup of fluid in the pleural can create a feeling of fullness and pressure, causing areas of pain in the chest cavity and sometimes in the lower back area. Chest pain occurs more often on the right side of the body, as mesothelioma affects the right lung 60% of the time. Only 5% patients suffer from mesothelioma in both lungs.

    In some cases, a patient may also have chronic hoarseness, difficulty swallowing (dysphagia) and/or the coughing up of blood (hemoptysis). These are the rare symptoms of mesothelioma and seen in less than 1% mesothelioma patients. If the patient also suffers from swelling of the face or neck areas, it means that the cancer has spread beyond the mesothelium.

    Peritoneal Mesothelioma

    The other type of mesothelioma is peritoneal which attacks the lining of the stomach or the abdominal cavity. It can cause symptoms like:

  • Belly Pain
  • Nausea
  • Vomiting
  • Weight loss
  • Fever
  • Night sweats
  • Frequency of urination
  • Bowel obstruction
  • Abdominal pain and swelling due to a buildup of fluid in the abdomen also known as ascites is one of the symptoms of peritoneal mesothelioma. If there is a tumor in the peritoneum membrane, it can put increasing pressure on the organs in the abdomen, leading to bowel obstruction and distention.

    Pericardial Mesothelioma

    The third type of mesothelioma is pericardial mesothelioma which attacks the lining of the chest cavity. It is not a common type of cancer. It can cause symptoms like:

  • Heart palpitations
  • Chest pains
  • Shortness of breath
  • Persistent cough
  • Weight loss
  • Irregular heartbeat
  • Pericardial effusion may also occur in pericardial mesothelioma. It is the accumulation of liquid in the lining of the chest cavity which may cause difficulty in breathing and shortness of breath. The patient may also complain of irregular heartbeat which is caused due to liquid accumulation in the chest. Persistent cough along with blood may also occur. Pericardial mesothelioma can also lead to lung cancer.

    Some of these symptoms can help you identify mesothelioma. Some patients show no symptoms of their mesothelioma which makes it more difficult to diagnose. The exact symptoms will often depend on the area where mesothelioma affects which will help you identify mesothelioma.